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InChiKey: RIIKDGPBTPECSW-UHFFFAOYSA-N
for 3 months) treatment significantly delays the progression of glomerulonephritis and increases the survival rate of NZB/W F1 mice
Protein binding is higher for GSK369796 Dihydrochloride (compound 4) compare to desethyl amodiaquine in the mouse (93 vs 74%) but similar in human (88 vs 86%)
PCI-33380 bound to Btk could be detected by denaturing gel electrophoresis and fluorescent gel scanning
Formula: C25H25F3N4O6
FIIN-3 esine Hydrochloride InChiKey: RIIKDGPBTPECSW-UHFFFAOYSA-NFIIN 3 is an irreversible inhibitor of FGFR with an IC50 of 13. 1, 21, 31. 4, and 35. 3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Product information CAS Number: 1637735 84 2 Molecular Weight: 691. 61 Formula: C34H36Cl2N8O4 Chemical Name: N (4 {[3 (6 {[4 (4 methylpiperazin 1 yl)phenyl]amino}pyrimidin 4 yl)[(2,6 dichloro 3,5 dimethoxyphenyl)carbamoyl]amino]methyl}phenyl)prop 2 enamide Smiles: