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UbcH5c-IN-1 avolitinib Germline and somatic SMARCA4 mutations

SKU: 10016525018

4.3
USD100.00 USD143.00

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Description

Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary

Formula: C21H20ClNO5

InChi: InChI=1S/C25H25N3O2S/c29-22(18-4-2-1-3-5-18)28-24-27-20-7-6-19(11-21(20)31-24)26-23(30)25-12-15-8-16(13-25)10-17(9-15)14-25/h1-7

Solubility: DMSO : ≥ 48 mg/mL (159

Solubility: DMSO : 30 mg/mL (80

UbcH5c-IN-1 avolitinib Germline and somatic SMARCA4 mutationsUbcH5c IN 1 (compound 6d) is a potent and selective small molecule inhibitor of Ubiquitin conjugating enzyme UbcH5c, with a Kd of 283 nM for E2 UbcH5c IN 1 by covalent binding with Cys85. A promising lead compound for the development of new antirheumatoid arthritis (RA) agent. Product information CAS Number: 2123480 72 6 Molecular Weight: 413. 30 Formula: C22H21BrO3 Chemical Name: (3aS,9bR) 8 [(2 bromophenyl)methoxy] 6,9 dimethyl 3 methylidene

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